Diabetesrelated causes of hyperpigmented patches of skin list of 28 causes of hyperpigmented patches of skin this section shows a full list of all the diseases and conditions listed as a possible cause of hyperpigmented patches of skin in our database from various sources. Melasma an example of hyperpigmentation is melasma. A 55yearold ghanaian woman presented with a 1year history of worsening hyperpigmentation of the skin on the arms, chest, face and buttocks. The term melasma is derived from the greek word melas, meaning black. A hyperpigmented patch that remains despite washing with soap. Differential diagnosis of acquired hyperpigmented macules is. Hyperpigmented patches on a womans sunexposed face. Hyperpigmentation may be the sign of a benign or relatively easily treated condition, or it may indicate the presence of a lifethreatening condition such as melanoma.
Pityriasis versicolor is characterized by scaly hypopigmented or hyperpigmented macules patches, most commonly affecting areas of skin that are rich in sebum production, such as the upper arms, neck, and trunk. Neonatal and infantile common skin lesions pediatrics. Postinflammatory hyperpigmentation presents as hyperpigmented macules patches in the area of the preceding inflammatory dermatosis or. Alan menter, md 1 1 from the division of dermatology, department of internal medicine, baylor university medical center, dallas, texas cather and menter. For people with darker skin, hypopigmentation may also result in stigma. Benign pigmented skin lesions, such as melanocytic naevi moles, seborrhoeic keratoses and lentigines. It occurs primarily in pregnant women melasma gravidarum, or the mask of pregnancy and in women taking oral contraceptives. Synonyms include chloasma and mask of pregnancy when it arises during pregnancy. A patch is a large macule equal to or greater than either 5 or 10 mm across, depending on ones definition of a macule. Less frequently, it may be caused by the deposition in the dermis of endogenous or exogenous pigments, such as hemosiderin, iron, or heavy metals. It doesnt involve any change in the thickness or texture of the skin. Patches may have some subtle surface change, such as a fine scale or wrinkling, but although the consistency of the surface is changed, the lesion itself is not palpable. Vitiligo presents with completely depigmented macules and patches as opposed to hypopigmented lesions.
Linear and whorled nevoid hypermelanosis has been associated with serious congenital defects, and a set of investigations, including brain magnetic resonance imaging, should be considered in this setting. In this patient, the macule partially overlaps the slategrey patch 9 oclock position on the upper thigh. Hypopigmentation can be upsetting, particularly if visible. Hyperpigmentation dermatologic disorders merck manuals. Common pigmentation disorders american family physician. Hyperpigmentation can also be caused by various drugs, including some antibiotics, antiarrhythmics, and antimalarial drugs. It is a commonly observed skin condition that is seen in many children and adults. Rashes can have macules, patches flat spots at least 1 cm in size. Common skin disorders of the penis wiley online library. When the spots first appeared, they were reddishpurple in color and mildly itchy. The pigmentation had developed approximately 10 years. Hypopigmented macules and patches clinical advisor. Hyperpigmentation as a peculiar presentation of mycosis fungoides.
The cause of hyperpigmentation usually is traced to the activity and presence of melanocytes. Eventually a hypopigmented halo develops after a prolonged duration of disease. Hyperpigmentation as a peculiar presentation of mycosis. Many hypopigmented macules are transient, and are caused by abnormal local vasoconstriction, as in the patient above. Pubmed is a searchable database of medical literature and lists journal articles that discuss macules hereditary congenital hypopigmented and hyperpigmented. The clinical differential diagnosis includes erythema dyschromicum perstans, lichen planus pigmentosus, drug eruption, and postinflammatory hyperpigmentation. Waxman, lisa, md the american journal of dermatopathology. Mf is an uncommon clinical variant of mf characterized by hypopigmented macules. Typically, lesions arise as multiple small, circular macules that enlarge radially and coalesce into patches. Hypopigmentation can be upsetting to some, especially those with darker skin whose hypopigmentation marks are seen more visibly. Diagnosis of some common and uncommon hyperpigmentation. Ten percent of cases occur in nonpregnant women and darkskinned men. Calm may have the color of coffee with milk in lighter skinned individuals but in darker skinned persons the color may be more medium to dark brown. Herein, we describe a patient with several hyperpigmented macules and patches on the trunk and right leg for 7 years previously.
Asymptomatic hyperpigmented macules and patches on the. Review of symptoms is negative for anything obviously contributory. Skin cancers, such as melanoma and pigmented basal cell carcinoma. Erythrasma will fluoresce coralred on wood lamp illumination rather than the characteristic. The evolution with hyperpigmented macules or patches is the main feature for. Localised pigmentation may be due to melanin, haemosiderin or externallyderived pigment.
Hereditary congenital hypopigmented and hyperpigmented macules. Physical examination revealed a pebbly, hyperpigmented plaque with minimal scale on the extensor surfaces of both arms and smooth, hyperpigmented patches on her upper chest, face and buttocks. Cal spots present as uniform tanbrown round or oval macules with distinct. Postinflammatory hyperpigmentation presents as hyperpigmented maculespatches in the area of the preceding inflammatory dermatosis or. Hyperpigmented macules and streaks jennifer clay cather, md, 1 mark r. Congenital hypomelanotic and hypermelanotic macules. Macules can be seen on any part of the body, but are most frequently found on the chest, back, face, and arms. Hyperpigmented patch on the leg mdedge dermatology. Asymptomatic hyperpigmented macules and patches on the trunk. Hyperpigmentation is the darkening or increase in the natural color of the skin, usually due to an increased deposition of melanin hypermelanosis in the epidermis andor dermis. Recurrent episodes of genital herpes are characteristically less. Occasionally, in the early active stage of the disease, elevated erythematous borders are noted surrounding the hyperpigmented macules. Bluish gray hyperpigmentation on the face and neck. Postinflammatory hyperpigmentation presents as irregular, darkly pigmented macules and patches at sites of previous injury or inflammation.
Hypopigmentation is common and approximately one in twenty have at least one hypopigmented macule. A 45yearold woman presented with brownish macules and patches on her face. A macule is a flat, distinct, discolored area of skin less than 1 centimeter cm wide. The hyperpigmentation is composed of homogeneous macules that coalesce into reticulated patches. Clinically, true primary genital herpes appears as macules and papules, followed by vesicles, pustules and ulcers 7. Hypopigmented macule hypopigmented macules are typically very subtle, and benign, findings in the newborn. Light brown patch that develops an increasing number of pigmented macules or papules, representing junctional or compound nevi. Some of the common causes of hyperpigmented patches of skin may include. For example, macules can be moles which are hyperpigmented. Its characterized by small patches of dark skin on the penis. Systemic complaints including fever, myalgias and lethargy may be present, but are rare in men. Hyperpigmented mycosis fungoides is among the rarest variant of mf, manifested as hyperpigmented macules or patches without poikilodermatous changes such as epidermal atrophy and telangiectasias. A 32yearold male with a past medical history of recurrent t12l1 leftsided schwannoma presented with a 1year history of a hyperpigmented lesion in the midlower back figures 1 and 2, left to right. Early ctcl often lacks the histologic criteria necessary for a definitive diagnosis.
Mycosis fungoides is a cutaneous tcell lymphoma that clinically presents as a single or multiple hypopigmented or hyperpigmented patches or as erythematous scaly lesions in. Macules may be a sign of something serious or mean absolutely nothing at all. Patients will often have accompanying tender lymphadenitis. Asymptomatic hyperpigmented macules and patches on the trunk torresromero, luis f. Melasma is an acquired disorder of hypermelanosis characterized by symmetrically distributed hyperpigmented macules patches involving sunexposed areas, primarily on the face. Macules hereditary congenital hypopigmented and hyperpigmented. If you have darker colored areas on your skin this is hyperpigmentation. Postinflammatory hyperpigmentation due to various inflammatory dermatoses occasionally displays a reticulate pattern. Melasma consists of dark brown, sharply marginated, roughly symmetric patches of hyperpigmentation on the face usually on the forehead, temples, cheeks, upper lip, or nose. Most causes of hypopigmentation are not serious and can be easily treated. Mostly affects fullterm african american infants 4. Penile melanosis is usually a benign or harmless condition. Diagnosis, hyperpigmentation, melanosis, pigmentation disorders.
Additionally, it usually affects younger patients and is more predominant in darkskinned. Melanotic macules of oral mucosa are observed on the lips, in the mouth, on the tongue, etc. They may be hypopigmented lighter than the surrounding skin, hyperpigmented darker than the surrounding skins, or appear pink or red. No other lesions are noted, and there is no lymphadenopathy. This change in color is known as hyperpigmentation. What caused this hyperpigmented reticulated rash on this.
Approach to reticulate hyperpigmentation vachiramon. The patient stated he has had severe back pain associated with the schwannoma and has been using a heating pad for relief every evening for at least 8 hours. Isolated hyperpigmented patches were also observed. The mongolian spot is a hyperpigmented macule or patch present at birth or. If dark patches are observed, the main diagnoses to consider are.
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